Education
2000
PhD ès Natural Sciences
University of Zurich, Switzerland
“Protein-assisted pyridoxal catalysis : engineering of enzymes and catalytic antibodies”
1992
Master in Enzymology, Physico-chemistry and Protein Engineering
University of Paris 11, Orsay, France
“Study of the folding and stability of a mutant of yeast phosphoglycerate kinase”
Professional experience
University of Nantes, Nantes, France
2022 - present
Immunology and new concepts in immunotherapy – INCIT, UMR Inserm 1302, EMR CNRS 6001
“Development and study of Affitins for diagnostic and targeted therapies”
2012 - 2021
Associate Professor (MCU Univ. Nantes)
Centre de Recherche en Cancérologie et Immunologie de Nantes Angers – CRCINA, Inserm 1232, CNRS ERL 6001
“Engineering of vectors for molecular imaging and therapy”
2006 - 2011
Associate Professor (MCU Univ. Nantes)
Biocatalyse, Biotechnologies et Biorégulation – U3B, CNRS UMR6204
“Exploration of the potential of Affitins for applications”
Pasteur Institute, Paris, France
2005
Post-doctoral fellow
Biochimie structurale, CNRS URA 2185, Institut Pasteur, Paris, France
“In vitro directed evolution of a DNA-binding protein and selection of protein ligands for co-crystallization”
2000-2002
Post-doctoral fellow
Laboratoire d’ingénierie des anticorps, Institut Pasteur, Paris, France
“Functional study of catalytic antibodies associated with systemic lupus erythematosus”
CNRS, Gif sur Yvette, France
2002-2004
Post-doctoral fellow
Laboratoire d’Enzymologie et Biochimie Structurales, CNRS LEBS, Gif-sur-Yvette
“Cellular traffic regulation: the role of the major protein exchange factors G Arf”
Grant: Human Frontier (HFSP)
